MicroLine is our proprietary pilocarpine formulation and candidate for the episodic treatment of presbyopia. We plan to begin our VISION Phase III study in 2020.
Pilocarpine has been demonstrated to constrict the pupil of the eye and create a “pinhole” effect, which like a pinhole camera, works to bring near and medium-distance objects into focus. This pinhole approach has been used in contact lenses and surgical approaches for presbyopia to improve near vision in patients with presbyopia, and now with MicroLine, Eyenovia looks towards improving near vision with it’s microdosed drug.